Prof. Bell Receives NIH R01 Grant

Prof. Bell received a $1.5M NIH R01 grant from the National Institute of Biomedical Imaging and Bioengineering to support our project entitled, Photoacoustic Image Guidance of Hysterectomies. This project is motivated by the clinical challenges surrounding ureteral injury during hysterectomies, due to the close proximity of uterine arteries (which must be severed) and ureters (which must be preserved). Complications from accidental ureteral injuries include extensive repeat surgeries, complete kidney failure, sepsis, acute renal insufficiency, and patient death. The goal of this project is to establish optimal parameters to advance photoacoustic technology toward differentiation of ureters, uterine arteries, and tool tips during hysterectomies. This work will be completed in collaboration with primary co-investigator, Karen Wang, MD.

Four of our pioneering publications in this area include:

  • Wiacek A, Wang KC, Wu H, Bell MAL, Photoacoustic-guided laparoscopic and open hysterectomy procedures demonstrated with human cadavers, IEEE Transactions on Medical Imaging, 40(12):3279-3292, 2021 [pdf]
  • Wiacek A, Wang KC, Wu H, Bell MAL, Parking sensor-inspired approach to photoacoustic-guided hysterectomy demonstrated with human cadavers, Proceedings of SPIE Photonics West, San Francisco, CA, March 6-11, 2021 [pdf]
  • Wiacek A, Wang KC, Bell MAL, Dual-wavelength photoacoustic imaging for guidance of hysterectomy procedures, Proceedings of SPIE Photonics West, San Francisco, CA, February 1-6, 2020 [pdf]
  • Wiacek A, Wang K, Bell MAL, Techniques to distinguish the ureter from the uterine artery in photoacoustic-guided hysterectomies, Proceedings of SPIE Photonics West, San Francisco, CA, February 2-7, 2019 [pdf]

This work was initially funded by a Johns Hopkins Discovery Award.

JHU Malone Center Announcement